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Related Concept Videos

Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

2.2K
Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists...
2.2K
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)00:53

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

2.0K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
2.0K
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)01:16

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

2.7K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
2.7K
Regioselectivity of Electrophilic Additions-Peroxide Effect02:35

Regioselectivity of Electrophilic Additions-Peroxide Effect

8.8K
In the presence of organic peroxides, the addition of hydrogen bromide to an alkene yields the isomer that is not predicted by Markovnikov’s rule. For example, the addition of hydrogen bromide to 2-methylpropene in the presence of peroxides gives 1-bromo-2-methylpropane. This addition reaction proceeds via a free radical mechanism, which reverses the regioselectivity. The free radical reaction mechanism involves three stages: initiation, propagation, and termination.
8.8K
Electrophilic Addition of HX to 1,3-Butadiene: Thermodynamic vs Kinetic Control01:23

Electrophilic Addition of HX to 1,3-Butadiene: Thermodynamic vs Kinetic Control

2.8K
The addition of a hydrogen halide to 1,3-butadiene gives a mixture of 1,2- and 1,4-adducts. Since more substituted alkenes are more stable, the 1,4-adduct is expected to be the major product. However, the product distribution is strongly influenced by temperature; low temperature favors the 1,2-adduct, whereas the 1,4-adduct is predominant at high temperature.
2.8K
Free-Radical Chain Reaction and Polymerization of Alkenes02:35

Free-Radical Chain Reaction and Polymerization of Alkenes

8.1K
The conversion of alkenes to macromolecules called polymers is a reaction of high commercial importance. The structure of the polymer is defined by a repeating unit, while the terminal groups are considered insignificant. The average degree of polymerization represents the number of repeating units in the polymer molecule and is denoted by the subscript n.
8.1K

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Related Experiment Video

Updated: Aug 28, 2025

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
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Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid

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Challenges Arising from Continuous-Flow Olefin Metathesis.

Antonio Del Vecchio1,2, Harry R Smallman3, Jennifer Morvan1

  • 1Univ Rennes, Ecole Nationale Supérieure de Chimie de Rennes CNRS, ISCR UMR 6226, F-35000, Rennes, France.

Angewandte Chemie (International Ed. in English)
|September 16, 2022
PubMed
Summary

Olefin metathesis in flow chemistry offers a powerful alternative to batch methods, improving synthesis and catalyst stability for industrial applications.

Keywords:
Continuous FlowHeterogeneous/Homogeneous CatalysisOlefin MetathesisReactor DesignRuthenium

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Area of Science:

  • Organic Chemistry
  • Chemical Engineering
  • Catalysis

Background:

  • Olefin metathesis is a versatile reaction with broad applications.
  • Flow chemistry presents an alternative to traditional batch processing.
  • Combining these fields addresses challenges in synthetic chemistry.

Purpose of the Study:

  • To survey the integration of continuous-flow methods with olefin metathesis.
  • To highlight advancements at the intersection of synthesis and reactor engineering.
  • To provide insights for the chemical and catalysis communities.

Main Methods:

  • Review of literature on continuous-flow olefin metathesis.
  • Analysis of techniques improving catalyst performance and reaction control.
  • Discussion of reactor design considerations for flow chemistry.

Main Results:

  • Continuous-flow olefin metathesis overcomes limitations of batch processes.
  • Improved control over self-reactions and catalyst deactivation (e.g., ethylene-mediated).
  • Enables more efficient and scalable synthetic routes.

Conclusions:

  • Flow chemistry enhances olefin metathesis for industrial relevance.
  • This approach offers significant advantages in catalysis and process engineering.
  • The review serves as a guide to emerging techniques in continuous processing.