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Comparative analysis between mono approach and multi approaches in managing T2DM: a survey-based study.

M Alanazi1, A Unnisa, R D Patel

  • 1Department of Clinical Pharmacy, Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, Kingdom Saudi Arabia. drunnisa.aziz10@gmail.com.

European Review for Medical and Pharmacological Sciences
|September 16, 2022
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Summary

Adding diet modification and regular exercise to oral agents significantly improves Type 2 Diabetes Mellitus (T2DM) management. These lifestyle changes enhance Fasting Blood Sugar (FBS) and HbA1c levels, supporting their integration into T2DM guidelines.

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Area of Science:

  • Endocrinology and Metabolism
  • Public Health and Epidemiology

Background:

  • Type 2 Diabetes Mellitus (T2DM) management often involves oral agents.
  • The role of lifestyle interventions like diet and exercise alongside oral agents requires further analytical comparison.

Purpose of the Study:

  • To analytically compare the therapeutic effect of adding diet modification and regular exercise to oral agents for T2DM management.

Main Methods:

  • A cross-sectional study surveyed 1248 participants using questionnaires on diabetes management.
  • Participants were classified into three groups based on single or multi-approach management strategies.
  • Diagnostic criteria included morning Fasting Blood Sugar (FBS) and glycated Hemoglobin (HbA1c).

Main Results:

  • A significant association was found between management strategies and lowered FBS and HbA1c (p=0.000).
  • Group 3, utilizing multi-approach management including diet and exercise, showed a strong association with improved FBS and HbA1c (p=0.000).
  • Diet modification was implemented by 836 participants, with 325 on moderate to severe modifications.

Conclusions:

  • Diet modification and regular exercise significantly improve FBS and HbA1c levels in T2DM patients.
  • These lifestyle interventions can serve as effective adjuvants to oral agents.
  • Incorporating diet and exercise into T2DM management guidelines is recommended.