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Working hard to avoid: Fixed-ratio response effort and maladaptive avoidance in humans.

Simon Dymond1,2, Weike Xia1, Keith Lloyd3

  • 1School of Psychology, Swansea University, Swansea, UK.

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|September 16, 2022
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Summary

High response effort in avoidance learning, even for safe cues, leads to persistent anxiety and fear. This highlights the need for treatments targeting effortful avoidance in anxiety disorders.

Keywords:
Avoidanceanxietyextinctionfearfixed-ratio schedulesresponse prevention

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Area of Science:

  • Psychology
  • Neuroscience
  • Clinical Psychology

Background:

  • Maladaptive avoidance is a core feature of anxiety disorders.
  • Response effort's role in avoidance acquisition and extinction is understudied.
  • Understanding effortful avoidance may improve clinical treatments.

Purpose of the Study:

  • To investigate the impact of high versus low response effort on avoidance extinction and return.
  • To examine the role of fixed-ratio (FR) schedules in maintaining avoidance behavior.
  • To assess fear and threat expectancy associated with effortful avoidance.

Main Methods:

  • Two laboratory-based studies using a multi-cue avoidance paradigm.
  • Response effort operationalized via fixed-ratio (FR) reinforcement schedules.
  • Measures included behavior, self-report, and physiological responses (skin conductance).

Main Results:

  • High response-effort avoidance persisted across both danger and safety cues.
  • Sustained and reinstated fear and threat expectancy were observed.
  • Skin conductance responses were similar across experiments, regardless of effort.

Conclusions:

  • High response effort contributes to extinction-resistant avoidance in humans.
  • Effortful avoidance, even for safety cues, maintains fear and threat.
  • Findings have implications for translational research and treatment development for anxiety.