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Cut it out! A CRISPR-Cas9 screen identifies host regulators of the Plasmodium liver stage
Michael E Chirgwin1, Erin A Schroeder2, Emily R Derbyshire3
1Department of Chemistry, Duke University, Durham, NC, USA.
Cell Chemical Biology
|September 16, 2022
Abstract:
In this issue of Cell Chemical Biology, Vijayan and colleagues identify host factors integral for Plasmodium liver-stage infection using a whole-genome CRISPR-Cas9 knockout screen. Their efforts reveal that liver-stage parasites redistribute host microtubules to the parasite membrane in a process dependent on the host Golgi.

