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The Geographical Correlation Between Historical Preterm Birth Disparities and COVID-19 Burden.
Ponnila S Marinescu1, Courtney Olson-Chen2, J Christopher Glantz2
1Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 668, Rochester, NY, 14642, USA. Ponnila_Marinescu@urmc.rochester.edu.
Pre-existing preterm birth (PTB) disparities geographically correlate with higher SARS-CoV-2 (COVID-19) infection rates. Areas with high COVID-19 prevalence showed increased PTB, linked to poverty and lower education.
Area of Science:
- Public Health
- Epidemiology
- Social Determinants of Health
Background:
- SARS-CoV-2 (COVID-19) infection rates vary geographically, mirroring disparities seen in obstetric outcomes.
- Pre-existing regional inequalities in preterm birth (PTB) may indicate areas vulnerable to disease burden.
Purpose of the Study:
- To investigate the geographical correlation between historical preterm birth (PTB) disparities and subsequent COVID-19 disease burden.
- To understand how social determinants of health influence the distribution of COVID-19.
Main Methods:
- Retrospective ecological cohort study using upstate New York birth certificate data (2004-2018) and 2020 COVID-19 rates.
- ZIP codes categorized into low, moderate, and high COVID-19 prevalence groups.
- Analysis of PTB rates correlated with poverty and educational attainment data; GIS mapping used for visualization.
Main Results:
- A positive correlation was found between PTB (all, <28 weeks, and periviable) and COVID-19 prevalence.
- High COVID-19 prevalence ZIP codes exhibited the highest PTB rates.
- Odds of PTB <28 weeks were significantly higher in high COVID-19 prevalence areas (OR 3.27).
- COVID-19 prevalence associated with poverty and inversely with income and education.
Conclusions:
- Historical disparities in preterm birth, reflecting social determinants of health, align with COVID-19 disease burden distribution.
- Socioeconomic policies addressing economic disparities are crucial for improving health outcomes in vulnerable communities.
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