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Elderly-Onset Paroxysmal Kinesigenic Dyskinesia: A Case Report
Lulu Yao1, Wei Liang1, Shanshan Mei2,3
1Department of Traditional Chinese Medicine, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Neurology and Therapy
|September 17, 2022
Summary
This case report details the first instance of elderly-onset paroxysmal kinesigenic dyskinesia (PKD), a condition causing sudden involuntary movements. Early diagnosis and oxcarbazepine treatment effectively managed the patient's symptoms.
Area of Science:
- Neurology
- Movement Disorders
Background:
- Paroxysmal kinesigenic dyskinesia (PKD) typically presents earlier in life.
- Distinguishing PKD from other paroxysmal conditions like epilepsy is crucial.
Purpose of the Study:
- To report the first case of elderly-onset paroxysmal kinesigenic dyskinesia (PKD).
- To highlight the diagnostic challenges and effective management of late-onset PKD.
Main Methods:
- Clinical case presentation of an elderly female with paroxysmal limb rigidity.
- Diagnostic workup included video-electroencephalogram (EEG) monitoring, MRI, FDG-PET/CT, and genetic testing.
- Treatment with oxcarbazepine.
Main Results:
- The patient presented with symptoms initially suspected as epilepsy but later diagnosed as PKD.
- Extensive diagnostic tests, including EEG, MRI, PET/CT, and genetic testing, were unremarkable.
- Symptoms significantly improved with oxcarbazepine treatment.
Conclusions:
- This case expands the known age range for PKD onset.
- Accurate differentiation from reflex epilepsy and hysteria is vital.
- A standard diagnostic approach is recommended for efficient PKD diagnosis and to prevent misdiagnosis.
