Related Experiment Video

Updated: Aug 28, 2025

P50 Sensory Gating in Infants
12:55

P50 Sensory Gating in Infants

Published on: December 26, 2013

9.3K

The Effect of CRHBP rs10062367 Polymorphism and Parenting Styles on Internalizing Problems in Preschoolers: The

Siyao Zeng1,2, Cuizhen Liu1,2, Zhenhong Wang3,4

  • 1School of Psychology, , Shaanxi Normal University, Shaanxi Provincial Key Research Center of Child Mental and Behavioral Health, Xi'an, China.

Child Psychiatry and Human Development
|September 17, 2022
PubMed

Insights

Preschoolers with high sensory processing sensitivity (SPS) and a specific gene variant (CRHBP rs10062367 A allele) show fewer internalizing problems with positive parenting but more with negative parenting.

Area of Science:

  • Child Psychology
  • Behavioral Genetics
  • Developmental Neuroscience

Background:

  • Parenting styles and genetic predispositions influence child behavior.
  • Sensory Processing Sensitivity (SPS) is a trait linked to environmental sensitivity.
  • Internalizing problems in preschoolers require understanding of interacting factors.

Purpose of the Study:

  • To investigate the interplay between CRHBP rs10062367 polymorphism, parenting styles, and SPS in preschoolers.
  • To determine how these factors predict internalizing problems.
  • To test the Differential Susceptibility Model/Biological Sensitivity to Context Theory.

Main Methods:

  • Genotyping of the CRHBP rs10062367 polymorphism in 446 preschoolers.
  • Parental questionnaires assessing parenting styles, child SPS, and internalizing problems.
  • Statistical analysis of gene-environment-behavior interactions.

Main Results:

  • High SPS preschoolers with the CRHBP rs10062367 A allele showed fewer internalizing problems under positive parenting.
  • The same group exhibited increased internalizing problems under negative parenting conditions.
  • This suggests a gene-environment interaction influencing emotional regulation.

Conclusions:

  • The CRHBP rs10062367 A allele and high SPS may act as susceptibility markers for environmental influences.
  • Findings support the Differential Susceptibility Model/Biological Sensitivity to Context Theory.
  • Understanding these interactions is crucial for targeted interventions in early childhood.

Keywords:
CRHBP rs10062367 polymorphismGene-environmentInternalizing problemsParenting stylesSensory processing sensitivity

More Related Videos

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

16.6K
Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood08:09

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood

Published on: February 11, 2017

11.6K

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
170
Parenting Styles01:27

Parenting Styles

Diana Baumrind's four parenting styles — authoritarian, authoritative, neglectful, and permissive — each influence children's socio-emotional development differently.
Authoritarian Parenting
This style is strict and controlling, with little room for open dialogue. Authoritarian parents demand obedience and often enforce rules with minimal warmth. Children raised this way may lack social skills and initiative, usually comparing themselves to others unfavorably.
Authoritative...
115
Socioemotional Development during Infancy01:30

Socioemotional Development during Infancy

Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
Primary Temperament Types
104
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
191
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
692
Information Processing Approach01:30

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
135