A novel spectrophotometric method based on plasmonic nanoparticles for nicotine detection.

Area of Science:

• Analytical Chemistry
• Materials Science

Background:

• Plasmonic nanoparticles (gold and silver) exhibit unique properties suitable for sensitive analytical method development.
• Localized Surface Plasmon Resonance (LSPR) is a key phenomenon utilized in nanoparticle-based detection.

Purpose of the Study:

• To propose a novel spectrophotometric method for nicotine detection utilizing plasmonic nanoparticles.
• To optimize experimental conditions for enhanced sensitivity and accuracy.

Main Methods:

• Development of a spectrophotometric method employing gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs).
• Optimization of experimental variables including solvent type and pH.
• Characterization of LSPR absorption bands at 395.5 nm for AgNPs and 543.5 nm for AuNPs.

Main Results:

• Achieved a low detection limit of 0.001 µM for AuNPs and 0.09 µM for AgNPs.
• Established analytical calibration curves with high linearity (R² = 0.9903 for AgNPs, R² = 0.9960 for AuNPs) across specified nicotine concentration ranges.
• Demonstrated good stability and selectivity of the proposed methods.

Conclusions:

• The developed nanoparticle-based spectrophotometric methods provide a sensitive and selective approach for nicotine detection.
• The methods exhibit excellent analytical performance, including low detection limits and high linearity.
• This technique holds promise for various analytical applications requiring precise nicotine quantification.