Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

261
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
261
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

463
Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
463
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

361
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
361
Stimulants01:29

Stimulants

285
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
285
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

899
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
899
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

319
CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its...
319

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Deleterious effects of heated tobacco on respiratory symptoms and lung function].

Revue des maladies respiratoires·2024
Same author

[Synthetic cannabinoid overdose: Watch out for acute respiratory complications].

Revue des maladies respiratoires·2024
Same author

[Bronchial diseases and heroin use. A systematic review].

Revue des maladies respiratoires·2023
Same author

[And if we wagered that 10 years from now, there will be no new "lungs and addictives substances" series in the Revue des Maladies Respiratoires?]

Revue des maladies respiratoires·2023
Same author

[Smoking cessation treatment for smokers with COPD: The importance of therapeutic education].

Revue des maladies respiratoires·2023
Same author

[Diffuse alveolar hemorrhage in cannabis smokers. A systematic literature review].

Revue des maladies respiratoires·2023

Related Experiment Video

Updated: Aug 28, 2025

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates
06:09

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Published on: May 30, 2025

267

[Inhaled marijuana and the lung, a toxic cocktail?]

P Pradère1, A M Ruppert2, G Peiffer3

  • 1Service de pneumologie, hôpital Marie Lannelongue, université Paris Saclay, groupe hospitalier Paris Saint Joseph, 92350 Le Plessis Robinson, France.

Revue Des Maladies Respiratoires
|September 17, 2022
PubMed
Summary
This summary is machine-generated.

Cannabis smoke harms the lungs, causing bronchitis, COPD, and emphysema, especially when combined with tobacco. It also negatively impacts lung function and may lead to a distinct lung cancer profile.

Keywords:
BPCOCOPDCannabisCessationJointLungPoumonSevrageSmoking

More Related Videos

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface
07:05

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

Published on: June 20, 2025

310
Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

150

Related Experiment Videos

Last Updated: Aug 28, 2025

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates
06:09

Development of a Preclinical Inhalation Model to Test Vaporized Cannabis Distillates

Published on: May 30, 2025

267
In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface
07:05

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

Published on: June 20, 2025

310
Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

150

Area of Science:

  • Pulmonology
  • Toxicology
  • Oncology

Background:

  • Cannabis smoke effects on respiratory health are debated, often confounded by tobacco co-consumption.
  • Joint smoke shares carcinogenic compounds with cigarette smoke, potentially damaging the respiratory epithelium.

Purpose of the Study:

  • To review the respiratory effects of cannabis smoke.
  • To highlight the association between cannabis smoking and lung cancer.
  • To emphasize the need for systematic screening and medical care.

Main Methods:

  • Literature review of studies on cannabis smoke and respiratory health.
  • Analysis of respiratory symptoms and lung function changes in chronic cannabis smokers.
  • Examination of the link between cannabis use and lung cancer characteristics.

Main Results:

  • Confirmed effects include aggravated chronic bronchitis, increased risk of COPD, emphysema, and pneumothorax.
  • Prospective studies show impaired lung function, including airway damage, DLCO alteration, and accelerated FEV1 decline.
  • Cannabis smoking is prevalent in young lung cancer patients, potentially indicating a more aggressive cancer profile.

Conclusions:

  • Cannabis smoke poses significant risks to lung health, comparable to tobacco smoke.
  • Systematic inquiry into cannabis consumption is crucial for patient care.
  • Further research is needed to understand cannabis's role in lung cancer development and treatment.