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[Local cholinergic agonists and paradoxal systemic reactions].
Journal Francais D'Ophtalmologie
|January 1, 1987
Summary
Two patients experienced paradoxical systemic reactions after pilocarpine and acetylcholine eye drops. One patient also showed epinephrine hypersensitivity, a rare combined manifestation, prompting a discussion on risk factors and an etio-pathological hypothesis.
Area of Science:
- Ophthalmology
- Pharmacology
- Clinical Medicine
Background:
- Systemic reactions to topical ocular medications can occur.
- Pilocarpine and acetylcholine are commonly used miotics in ophthalmology.
- Paradoxical reactions are rare but potentially serious adverse events.