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Updated: Aug 28, 2025

In Vitro Thrombosis Test for Ventricular Assist Devices
Published on: March 21, 2025
Intraoperative pump thrombosis (PT) in HeartMate (HM) III
Sathappan Karuppiah1, Sudharsan Setty1, Ranjit John2
1Department of Anesthesiology, University of Minnesota Medical Center, Minneapolis, Minnesota, USA.
Abstract:
Pump thrombosis (PT) is a rare and infrequent complication of HeartMate III left ventricular assist device (LVAD). While there are reports of PT in the postoperative period, to our knowledge, there have been no prior reports on PT in the intraoperative period. Here we present a case of a 24-year-old female who required HeartMate III LVAD implantation for progressive heart failure and the intraoperative period was complicated with PT. Managing PT in the intraoperative period is challenging and time-sensitive because of its rare occurrence and paucity of recommendations in diagnosing the PT.
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