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Related Experiment Video

Updated: Aug 28, 2025

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Brain microstructure abnormalities in the 3xTg-AD mouse - A diffusion MRI and morphology correlation study.

Maria Fatima Falangola¹, Xingju Nie¹, Joshua Voltin¹

¹Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA; Center for Biomedical Imaging, Medical University of South Carolina, Charleston, SC, USA.

Magnetic Resonance Imaging

|September 18, 2022

Summary

Diffusion MRI detects microstructural changes in a mouse model of Alzheimer's disease (AD). These diffusion MRI (dMRI) changes correlate with amyloid-beta and tau pathology, showing potential as AD biomarkers.

Failed At:

2026-06-19T13:48:53.736397+00:00

Keywords:

3xTg-AD mouse Alzheimer's disease Diffusion MRI Diffusional kurtosis imaging

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