Results of a sensibility test on bacteria in developing countries

Area of Science:

• Microbiology
• Infectious Diseases
• Public Health

Background:

• Pathogenic germs pose a significant threat to human and animal health globally.
• Surveillance of microbial contamination in diverse environments is crucial for public health.
• Antimicrobial resistance necessitates ongoing evaluation of therapeutic efficacy.

Purpose of the Study:

• To identify and characterize pathogenic germs in human, animal, and drinking water samples.
• To assess the susceptibility of isolated bacterial strains to various chemotherapeutics.
• To compare the effectiveness of different antimicrobial agents against prevalent pathogens.

Main Methods:

• Collection of samples including wound, throat, and vaginal swabs, stools, and feces/anal swabs from humans and animals.
• Isolation and identification of bacterial strains from all sample types.
• In vitro susceptibility testing of bacterial isolates against a panel of chemotherapeutics.

Main Results:

• Pathogenic germs were detected across human, animal, and drinking water sources in Sudan, Colombia, and Cape Verde.
• Gentamicin exhibited the most comprehensive antimicrobial activity against the tested bacterial strains.
• Co-trimoxazole demonstrated significant efficacy, ranking as the second-best therapeutic option.

Conclusions:

• The study highlights the presence of pathogenic bacteria in diverse ecological niches across the studied regions.
• Gentamicin is a highly effective chemotherapeutic agent against a broad spectrum of bacterial pathogens identified in this study.
• Co-trimoxazole remains a valuable treatment option, though less comprehensive than gentamicin.