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Persisting sicca complaints in sarcoidosis.
Benedikt Hofauer1, Miriam Wiesner1, Zhaojun Zhu1
1Department of Otorhinolaryngology/Head and Neck Surgery, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
Frontiers in Medicine
|September 19, 2022
Summary
Sicca symptoms like dry eyes and xerostomia persist in sarcoidosis patients long-term, unlike other salivary gland issues. This requires ongoing monitoring to prevent further oral and ocular complications.
Area of Science:
- Rheumatology
- Otorhinolaryngology
- Nephrology
- Pneumology
Background:
- Sarcoidosis is a systemic inflammatory disease.
- Extrapulmonary manifestations, including salivary gland involvement, are common.
- This study focuses on the long-term course of glandular symptoms, particularly persistent sicca symptoms.
Purpose of the Study:
- To analyze the long-term course of glandular symptoms in sarcoidosis patients.
- To investigate the persistence of sicca symptoms (dry eyes and xerostomia).
- To understand the implications for patient follow-up and management.
Main Methods:
- Retrospective analysis of sarcoidosis patients over 20 years.
- Clinical examinations and functional evaluation of salivary glands.
- Sonographic examination of salivary glands.
Main Results:
- 76 patients were included (mean age 35.1 years).
- At baseline, 32 had xerostomia and 36 had dry eyes.
- After ~88 months, xerostomia persisted in 29 and dry eyes in 35 patients, while other symptoms resolved.
Conclusions:
- Sicca symptoms significantly persist in sarcoidosis patients.
- Persistence of sicca symptoms is independent of therapy type.
- Ongoing monitoring for sicca symptoms is crucial to prevent ocular, oral, and dental damage.
Keywords:
elastographyhead and neckparotid glandsalivary glandssarcoidosissonographysubmandibular glandMore Related Videos
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