Follow-up study of pauci-bacillary leprosy on-multi-drug regimen

One hundred and twenty nine newly registered cases of pauci-bacillary leprosy were put on Dapsone daily and Rifampicin once a month and were followed up for one year. Out of 129 cases, 108 (83.7%) were found to be clinically active at the end of one year of multidrug treatment (MDT). In 25 out of these 108 cases, skin biopsy was done and well defined granulomas were seen after therapy in 11 patients (44%).