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Updated: Aug 28, 2025

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Swallowing Related Problems of Toddlers with Down Syndrome
1Faculty of Physical Therapy and Rehabilitation, Hacettepe University, 06100 Altındağ, Ankara, Turkey.
Insights
Toddlers with Down syndrome (DS) experience more chewing disorders, drooling, and coughing during swallowing than typically developing children (TDC). Early intervention for swallowing issues and caregiver support is crucial for children with DS.
Area of Science:
- Pediatrics
- Developmental Pediatrics
- Speech-Language Pathology
Background:
- Swallowing difficulties are common in children with Down syndrome (DS).
- Understanding these challenges is vital for early intervention and improving quality of life.
- Comparison with typically developing children (TDC) provides a benchmark for assessing these issues.
Purpose of the Study:
- To define and compare swallowing-related problems in toddlers with DS versus TDC.
- To assess the severity of dysphagia symptoms using the Pediatric version of the Eating Assessment Tool-10 (PEDI EAT-10).
- To evaluate the impact of swallowing disorders on caregivers using the Feeding/Swallowing Impact Survey (T-FS-IS).
Main Methods:
- A prospective study involving 127 toddlers (96 DS, 31 TDC) and their mothers.
- Assessment of chewing disorders, food selectivity, drooling, and coughing during swallowing.
- Utilized PEDI EAT-10 for dysphagia severity and T-FS-IS for caregiver impact.
Main Results:
- Mothers of children with DS reported significantly higher rates of chewing disorders, drooling, and coughing during swallowing compared to mothers of TDC (p < 0.01).
- Children with DS had higher mean PEDI EAT-10 scores, indicating greater dysphagia symptom severity (p = 0.006).
- Significant differences were found in T-FS-IS scores between the groups, with moderate to strong correlations between PEDI EAT-10 and T-FS-IS scores (p < 0.001).
Conclusions:
- Toddlers with Down syndrome exhibit distinct and more prevalent swallowing-related problems compared to their typically developing peers.
- Early identification of swallowing concerns in children with DS is essential.
- Addressing the impact on caregivers' quality of life is integral to managing swallowing problems effectively in this population.
Abstract:
The study was aimed to define swallowing related problems of toddlers with Down syndrome (DS) by comparing toddlers with typically developing children (TDC). A total of 127 children (96 DS, 31 TDC), and their mothers included in the study. The presence of chewing disorders, food selectivity, drooling, coughing during swallowing was scored as 'absent' or 'present'. The Pediatric version of the Eating Assessment Tool-10 (PEDI EAT-10) was used to determine dysphagia symptom severity, and the Turkish version of the Feeding/Swallowing Impact Survey (T-FS-IS) was used to measure the impact of swallowing disorders on caregivers. Mothers of DS reported higher rates of chewing disorders (n = 39, 40.6%), drooling (n = 30, 31.3%) and coughing during swallowing (n = 50, 41.7%) than mothers of TDC (p < 0.01). The mean PEDI-EAT-10 score of children with DS was higher than TDC (p = 0.006). There were significant differences between groups in terms of T-FS-IS. Moderate to strong correlations were detected between PEDI-EAT-10 and total and subscale scores from T-FS-IS (p < 0.001). This prospective study defines swallowing related problems of toddlers with DS. The study results highlight the importance of early investigation of (i) swallowing concerns in children with DS, and (ii) caregivers' quality of life to define swallowing problems and plan an appropriate swallowing related management program.
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