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Updated: Aug 28, 2025

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
Renal Cell Carcinoma with Cardiac Metastases: A Case Report and Review of the Literature
Ellen M Cahill1, Alexandra Tabakin1, Brian Shinder1
1Section of Urologic Oncology, Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Insights
Cardiac metastases from renal cell carcinoma (RCC) are rare but can be extensive. This case details a patient with right atrial involvement, impacting the tricuspid valve and right ventricle, posing diagnostic and treatment challenges.
Area of Science:
- Oncology
- Cardiology
- Pathology
Background:
- Renal cell carcinoma (RCC) rarely metastasizes to the heart.
- Cardiac involvement presents unique diagnostic and therapeutic challenges.
Observation:
- A case of a woman with advanced RCC and extensive cardiac metastases is presented.
- Metastases involved the entire right atrium, penetrated the myocardium, and extended into the tricuspid valve and right ventricle.
Findings:
- The cardiac metastases demonstrated significant invasion and structural compromise.
- Diagnosis and management required a multidisciplinary approach.
Implications:
- This case underscores the importance of considering cardiac involvement in advanced RCC.
- Further research into early detection and novel treatment strategies for cardiac metastases is warranted.
Abstract:
Cardiac metastases from renal cell carcinoma (RCC) are very rare. We describe the case of a woman with RCC with cardiac metastases involving the entire right atrium, penetrating through the myocardium, with extension into the tricuspid valve and right ventricle. This report highlights the unique challenge of the diagnosis and treatment of cardiac metastases in RCC.
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