Related Experiment Video
Updated: Aug 28, 2025
Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Risk stratification and in-hospital outcome in patients with acute coronary syndrome
Amitkumar V Bhalerao1, Sheikh Mohamad Tahir2, Rajiv Agarwal3
1Interventional Cardiologist, B.K.L Walawalkar Hospital, Diagnostic and Research Centre, Ratnagiri, Maharashtra, India.
Insights
Acute coronary syndrome (ACS) predominantly affects individuals aged 55-74. Hypertension and tobacco use are key risk factors, particularly for ST-elevation myocardial infarction (STEMI), with percutaneous intervention being the primary treatment.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Acute coronary syndrome (ACS), encompassing ST-elevation myocardial infarction (STEMI) and unstable angina (UA), represents a significant cause of mortality and morbidity.
- Coronary artery disease (CAD) management and outcomes in tertiary care settings require detailed demographic and risk factor analysis.
Purpose of the Study:
- To define the demographic profile of ACS patients in a tertiary care center.
- To identify prevalent risk factors associated with ACS.
- To evaluate in-hospital management and outcomes for ACS patients.
Main Methods:
- Retrospective analysis of patient data including sociodemographics, clinical history, and investigations.
- Data collection from Batra Hospital and Medical Research Center, New Delhi, India.
- Review of electrocardiogram (ECG), echocardiogram (ECHO), and coronary artery graft information.
Main Results:
- A statistically significant association was observed between age groups and ACS type (p=0.04), with most patients aged 55-74.
- Tobacco abuse was more prevalent in STEMI patients; hypertension and tobacco use were consistent risk factors for STEMI.
- Percutaneous intervention was the predominant treatment (69%), followed by coronary artery bypass graft (5%) and thrombolysis (5.7%).
Conclusions:
- STEMI showed a higher prevalence in younger patients, though less pronounced in older individuals.
- Conventional risk factors were present across all ACS types, with hypertension and tobacco abuse being particularly notable for STEMI.
- Treatment strategies varied significantly based on ACS type, highlighting the need for tailored management approaches.
Background:
Death and morbidity are caused by coronary artery disease (CAD) and acute coronary syndrome (ACS), which include ST-elevation myocardial infarction (STEMI) and unstable angina (UA), are the most common causes of death among those with CAD. The aim of the study was to define the demographic profile of patients with ACS in a tertiary care center, to identify risk factors in the profile of patients with ACS, to learn about the management of ACS in tertiary health care centers, and to estimate in-hospital outcomes in ACS patients at a tertiary health care center.
Methods:
The study was carried out in the Cardiology Department of Batra hospital and Medical Research Center, New Delhi, India. The Research Ethics Committee of the Hospital reviewed and approved the study protocol.
Data Collected Included:
Sociodemographic data, anthropometric data, clinical history, significant past medical history, medications, current clinical status of the patient, and investigations including electrocardiogram (ECG), electrocardiogram (ECHO), and coronary artery graft.
Results:
Age groups and type of ACS were having a statistically significant association (p = 0.04). A majority of patients with ACS were seen in the 55-74 years age group. Tobacco abuse was more common in STEMI patients as compared to other types of ACS. There was significant variation between risk stratification of ACS patients by Thrombolysis in Myocardial Infarction and Global Registry of Acute Cardiac Events scores. Single vessel disease (SVD) patients dominated both the STEMI [26 (50.9%)] and UA [13 (52%)] groups. There was a highly significant association between a specific line of treatment and type of ACS (p < 0.0001). A majority of patients underwent percutaneous intervention (69% of 100). Coronary artery bypass graft (CABG) was done in five (5/100) patients only. Thrombolysis was advocated in three (5.7%) patients with Streptokinase (SK) and two patients with Tenecteplase (TNK).
Conclusion:
There was a marked preponderance of STEMI in younger patients but it was less marked in older patients, according to the study. All conventional risk factors were represented in all types of ACS but hypertension and tobacco abuse were more consistent risk factors associated with STEMI.
More Related Videos
05:41Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Published on: December 16, 2022
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
Related Concept Videos
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:30Acute Coronary Syndrome I: Introduction
01:26Acute Coronary Syndrome V: Nursing Management
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
01:30Heart Failure IV: Classification and Diagnostic Evaluation