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Sharing Time-to-Event Data with Privacy Protection.

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Summary
This summary is machine-generated.

New TE-Sanitizer method protects sensitive time-to-event data from cohort inference attacks. This approach ensures data utility for survival analysis while safeguarding individual privacy against adversaries.

Keywords:
Provable PrivacySurvival AnalysisTime-to-event Data

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Area of Science:

  • Biostatistics
  • Data Privacy
  • Health Informatics

Background:

  • Sharing time-to-event data is crucial for collaborative research, intervention design, and patient care.
  • External information, such as social media disclosures, introduces new privacy risks to shared time-to-event data.
  • Existing privacy solutions may not fully protect against sophisticated inference attacks.

Purpose of the Study:

  • To formulate and investigate a cohort inference attack targeting time-to-event data sharing.
  • To evaluate the privacy effectiveness of current methods like binning and differential privacy.
  • To propose a novel method, TE-Sanitizer, for privately releasing high-utility time-to-event data.

Main Methods:

  • Formulation of a cohort inference attack scenario for time-to-event data.
  • Empirical evaluation of privacy risks and protection levels of existing privacy-preserving techniques.
  • Development and validation of the TE-Sanitizer method for private data release.

Main Results:

  • The study demonstrates significant privacy risks associated with time-to-event data sharing.
  • Popular privacy solutions show varying degrees of protection against inference attacks.
  • TE-Sanitizer effectively mitigates inference attacks while maintaining high data utility for survival analysis.

Conclusions:

  • TE-Sanitizer offers a robust solution for privacy-preserving release of individual-level time-to-event data.
  • The method provides strong indistinguishability guarantees, protecting against cohort inference.
  • Findings offer valuable insights for domain experts on balancing privacy and data usefulness in survival studies.