Giant mesenteric myxoid liposarcoma: Challenges of diagnosis and treatment

Myxoid liposarcoma is the most frequent form of liposarcoma, frequently localized in the extremities. Abdominal liposarcomas more commonly arise from the retroperitoneum. However, primary mesenteric localization is extremely rare. To the best of our knowledge, 22 cases have been reported in English literature. The diagnosis is often delayed by the insidious evolution of this tumor. On radiological examination, primary mesenteric liposarcoma presents as a large mass that entrapped the small bowel loops. The treatment requires complete tumor resection. We report an observation of mesenteric myxoid liposarcoma in a 64-year-old female patient, revealed by an abdominal mass associated with abdominal pain. The treatment consisted of complete tumor removal. Histologically, the tumor proved to be a myxoid liposarcoma. No adjuvant treatment was considered necessary. The patient recovered well after the operation. The aim of reporting this case is to present an uncommon clinical entity because of its huge dimensions, the rarity of the site, and histological pattern.