Anesthetic Considerations for a Patient with Autosomal Dominant Polycystic Kidney Disease, Having a Ruptured

Shalvi Mahajan1, Vidhya Narayanan2, Vikas Bhatia3

  • 1Division of Neuroanaesthesia, Department of Anaesthesia, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Insights

Autosomal dominant polycystic kidney disease (ADPKD) patients with intracranial aneurysms require careful anesthetic management. This case report details successful anesthetic strategies for a ruptured anterior communicating artery aneurysm treated with endovascular coiling.

Area of Science:

  • Nephrology
  • Neurology
  • Anesthesiology

Background:

  • Autosomal dominant polycystic kidney disease (ADPKD) affects 1 in 1,000 individuals globally.
  • Intracranial aneurysms are a significant extrarenal complication of ADPKD, occurring in 9-12% of patients.
  • Managing these aneurysms involves surgical clipping or endovascular coiling.

Observation:

  • Anesthetic management for ADPKD patients with intracranial aneurysms is not well-documented.
  • Chronic kidney disease in ADPKD complicates anesthetic care, especially with subarachnoid hemorrhage.
  • This report focuses on the anesthetic approach for a patient with ADPKD and a ruptured anterior communicating artery aneurysm.

Findings:

  • The patient with ADPKD and a ruptured anterior communicating artery aneurysm underwent successful endovascular coiling.
  • Specific anesthetic considerations were applied to manage the superimposed risks of ADPKD and subarachnoid hemorrhage.
  • The anesthetic plan facilitated the safe completion of the endovascular coiling procedure.

Implications:

  • Highlights the need for specialized anesthetic protocols for ADPKD patients undergoing aneurysm treatment.
  • Contributes to the limited literature on anesthetic management in this complex patient population.
  • Informs clinical practice for managing patients with concurrent ADPKD and intracranial aneurysms.

Related Concept Videos

Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
17
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
17
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
486
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
134
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
188
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
53