Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Focusing of Light in the Eye01:16

Focusing of Light in the Eye

3.1K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
3.1K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

628
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
628
Glaucoma: Overview01:25

Glaucoma: Overview

702
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
702

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Data Volume and the Need for Clinical Decision Support in Glaucoma Care.

Ophthalmology science·2026
Same author

Derivation and validation of clinical prediction models for viral etiologies of acute diarrhea in North American children presenting for emergency care.

medRxiv : the preprint server for health sciences·2026
Same author

Development and External Validation of a Prognostic Prediction Model for Hospitalization in SARS-CoV-2-Infected Ambulatory Patients.

Open forum infectious diseases·2026
Same author

Association between Weather Variables and Viral Gastroenteritis in the United States.

medRxiv : the preprint server for health sciences·2026
Same author

Integrative Clinical-Molecular Modeling Identifies <i>LRRN4CL</i> as a Determinant of Structural and Functional Myocardial Improvement.

bioRxiv : the preprint server for biology·2026
Same author

Impact of baseline medications on real-world overall survival in immune checkpoint inhibitor-treated patients with cancer in the RADIOHEAD cohort.

Med (New York, N.Y.)·2026

Related Experiment Video

Updated: Aug 28, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

509

Refractive error in unilateral Duane syndrome.

Marielle P Young1, Warassabhorn Ployprasith2, Ben J Brintz3

  • 1Moran Eye Center, Department of Ophthalmology, University of Utah, Salt Lake City, Utah.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|September 19, 2022
PubMed
Summary

Patients with Duane syndrome develop higher astigmatism, particularly oblique astigmatism, in affected eyes compared to unaffected eyes. This suggests extraocular muscles may influence refractive error development.

More Related Videos

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.7K
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

9.0K

Related Experiment Videos

Last Updated: Aug 28, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
05:46

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity

Published on: September 20, 2024

509
Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

2.7K
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

9.0K

Area of Science:

  • Ophthalmology
  • Strabismology
  • Refractive Error

Background:

  • Duane syndrome is a congenital eye movement disorder characterized by limited horizontal eye movement and often associated with abnormal innervation of the extraocular muscles.
  • Chronic co-contraction of the medial and lateral rectus muscles is a hallmark of Duane syndrome, potentially impacting ocular structures and visual development.

Purpose of the Study:

  • To investigate the relationship between chronic co-contraction of extraocular muscles in Duane syndrome and the development of against-the-rule astigmatism.
  • To compare refractive error, specifically astigmatism, between affected (Duane) eyes and unaffected (fellow) eyes in patients with unilateral Duane syndrome.

Main Methods:

  • A retrospective analysis of 4,103 patients diagnosed with Duane syndrome by Dr. Arthur Jampolsky was conducted.
  • Eighty-four patients with unilateral Duane syndrome and complete data sets were included, comparing refractive error between Duane and fellow eyes.

Main Results:

  • Duane eyes exhibited significantly higher mean cylinder power (0.7 D vs. 0.4 D) and were more likely to have any astigmatism (P=0.0005) compared to fellow eyes.
  • A modest increase in against-the-rule astigmatism (P=0.04) and a significant increase in oblique astigmatism (P=0.004) were observed in Duane eyes.
  • Spherical equivalents were similar between Duane and fellow eyes (0.4 D vs. 0.2 D, P=0.14).

Conclusions:

  • Duane syndrome is associated with increased astigmatism, particularly oblique astigmatism, in affected eyes.
  • These findings support the hypothesis that the mechanical forces exerted by extraocular muscles can influence the development of refractive errors like astigmatism.