Related Experiment Video
Updated: Aug 28, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Clinical reasoning by pharmacists: A scoping review
Josephine F Mertens1, Ellen S Koster2, Vera H M Deneer3
1Leiden University Medical Center, Department of Clinical Pharmacy and Toxicology, Postbus 9600, 2300 RC Leiden, the Netherlands.
This review maps pharmacist clinical reasoning, finding it a context-dependent cognitive process. Teaching clinical reasoning requires explicating transparent cognitive processes in decision-making.
Area of Science:
- Pharmacy Practice
- Cognitive Science
- Health Professions Education
Background:
- Clinical reasoning is a core competency for pharmacists.
- Lack of conceptual clarity complicates teaching and assessment of clinical reasoning.
- This scoping review examines cognitive processes and conceptualizations of clinical reasoning in pharmacists.
Purpose of the Study:
- To identify, map, and examine evidence on cognitive processes used by pharmacists.
- To understand the conceptualization of clinical reasoning in pharmacy practice.
- To inform teaching and assessment strategies for clinical reasoning.
Main Methods:
- Scoping review of primary research studies in seven databases (searched March 2021).
- Included studies examined cognitive processes in pharmacists during clinical scenarios.
- Descriptive analysis of study characteristics, conceptualizations, operationalizations, and findings, adhering to PRISMA extension for Scoping Reviews.
Main Results:
- Seventeen studies were included, focusing on diagnosis formation (9) or medication appropriateness (4).
- Clinical reasoning is conceptualized as a context-dependent cognitive process integrating knowledge and experience.
- Pharmacists use analytical and intuitive reasoning approaches, with analytical reasoning predominant in medication review.
Conclusions:
- Research on pharmacist clinical reasoning is growing.
- Clinical reasoning should be taught as a distinct stage of clinical decision-making.
- Explicit teaching and reflection on transparent cognitive processes are recommended.
More Related Videos
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
12:18A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Related Concept Videos
Drug Administration and Therapy Phases: Overview
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Critical Thinking II
Biopharmaceutics and Pharmacokinetics: Overview
Patient-centered Care