Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ovarian Cycle01:27

Ovarian Cycle

1.7K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
1.7K
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

32
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
32
Nondisjunction01:21

Nondisjunction

4.0K
Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
4.0K
Monohybrid Crosses01:20

Monohybrid Crosses

230.8K
Overview
230.8K
Meiosis I01:49

Meiosis I

194.1K
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by...
194.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Induction of labor in twin pregnancies: systematic review and meta-analysis.

Best practice & research. Clinical obstetrics & gynaecology·2026
Same authorSame journal

Non-immune causes of fetal anemia.

Best practice & research. Clinical obstetrics & gynaecology·2026
Same authorSame journal

A risk-based classification of late-onset fetal growth disorders according to intrapartum fetal compromise.

Best practice & research. Clinical obstetrics & gynaecology·2026
Same author

Moving beyond associations: The role of mechanistic evidence in prenatal paracetamol safety.

Med (New York, N.Y.)·2026
Same author

Maternal Group B <i>Streptococcus</i> Vaccination: A Three-Country European Consortium to Improve Surveillance and Data Readiness.

Clinical epidemiology·2026
Same author

Perinatal outcomes following single intrauterine death in monochorionic twin pregnancies complicated by twin anemia polycythemia sequence: Systematic review and meta-analysis.

Acta obstetricia et gynecologica Scandinavica·2026

Related Experiment Video

Updated: Aug 28, 2025

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

15.0K

Monochorionic monoamniotic twin pregnancies.

Delima Khairudin1, Asma Khalil2

  • 1Fetal Medicine Unit, Liverpool Women's Hospital, Liverpool, UK.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|September 19, 2022
PubMed
Summary
This summary is machine-generated.

Monochorionic monoamniotic (MCMA) twin pregnancies are rare and high-risk. Early surveillance can decrease fetal death risk, but optimal monitoring and delivery timing remain undefined.

Keywords:
MCMA twinMonoamniotic twinMonochorionic monoamniotic (MCMA) twin pregnancyMultiple pregnancy

More Related Videos

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

27.0K
Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

19.8K

Related Experiment Videos

Last Updated: Aug 28, 2025

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

15.0K
Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
09:52

Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

Published on: September 5, 2011

27.0K
Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

19.8K

Area of Science:

  • Maternal-Fetal Medicine
  • High-Risk Obstetrics
  • Perinatology

Background:

  • Monochorionic monoamniotic (MCMA) twin pregnancy is a rare condition with significantly higher complication rates compared to other twin gestations.
  • The absence of an inter-twin membrane in MCMA pregnancies leads to challenges like cord entanglement, fluctuating fetal positions, and difficulties in diagnosing twin-twin transfusion syndrome (TTTS).
  • Early detection of fetal anomalies, TRAP sequence, and conjoined twins is crucial, but evidence-based monitoring strategies for MCMA pregnancies are lacking.

Purpose of the Study:

  • To review the current understanding and challenges associated with monochorionic monoamniotic (MCMA) twin pregnancies.
  • To highlight the importance of early surveillance and its potential impact on reducing fetal demise.
  • To identify the gaps in evidence regarding optimal prenatal monitoring and delivery timing for MCMA twins.

Main Methods:

  • Review of existing literature and observational studies on MCMA twin pregnancies.
  • Analysis of diagnostic challenges, including TTTS detection without membrane visualization.
  • Evaluation of surveillance protocols and their impact on fetal outcomes.

Main Results:

  • While evidence is limited, observational studies suggest that initiating surveillance in MCMA pregnancies significantly decreases the risk of fetal death.
  • In-utero fetal demise in MCMA twins can be sudden and unpredictable, even with close monitoring.
  • Elective preterm delivery around 33 weeks via cesarean is often recommended when risks of continuing pregnancy outweigh prematurity risks.

Conclusions:

  • Monochorionic monoamniotic (MCMA) twin pregnancy requires careful management due to its inherent risks.
  • Early and consistent prenatal surveillance is associated with improved fetal survival rates.
  • Further research is needed to establish optimal surveillance protocols and delivery timing guidelines for MCMA twin pregnancies.