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Dedifferentiated liposarcoma found in ovary: A rare case report
Junyu Chen1, Lianying Ding1,2, Taiwei Wang3
1Departments of Gynecology and Obstetrics, The Second Hospital of Jilin University, Changchun, China.
Medicine
|September 20, 2022
Summary
Dedifferentiated liposarcoma (DL) of the ovary is a rare tumor. Surgical resection is key for treatment, with no recurrence observed 12 months post-surgery in this case.
Area of Science:
- Oncology
- Pathology
- Gynecologic Oncology
Background:
- Dedifferentiated liposarcoma (DL) is a rare ovarian mesenchymal tumor, challenging to diagnose preoperatively.
- Diagnosis relies on post-surgical morphology, immunohistochemistry, and FISH analysis.
Observation:
- A 63-year-old postmenopausal woman presented with a large pelvic mass, initially presumed to be an ovarian neoplasm.
- The mass was later identified as a dedifferentiated liposarcoma originating from the mesentery and developing within the ovary.
Findings:
- Complete surgical resection via bilateral salpingo-oophorectomy was performed.
- The patient remains recurrence-free 12 months post-operation.
Implications:
- Ovarian DL is exceptionally rare, with its precise origin sometimes ambiguous.
- While retroperitoneum is common, mesenteric origin is suspected in this case.
- Complete surgical resection is crucial for managing ovarian DL.

