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Morphological changes in the iridocorneal angle and their relationship with intraocular pressure after infantile
Dan-Dan Wang1,2, Zhang-Liang Li1,2, Bing Zhang1,2
1Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Insights
Pediatric cataract surgery can alter the iridocorneal angle, increasing trabecular meshwork pigmentation and iris processes. Intraocular pressure (IOP) changes correlate with these morphological shifts post-surgery.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Surgical Outcomes
Background:
- Pediatric cataract surgery is essential for visual development.
- Understanding post-surgical anatomical changes is crucial for managing potential complications.
- The iridocorneal angle's morphology can impact intraocular pressure (IOP).
Purpose of the Study:
- To evaluate morphological changes in the iridocorneal angle following pediatric cataract surgery.
- To analyze the relationship between IOP and these anatomical alterations.
Main Methods:
- A cohort of children undergoing primary infantile cataract surgery were included.
- Two gonioscopic examinations were performed: pre-operatively and before secondary intraocular lens implantation.
- Morphological features of the iridocorneal angle and IOP were assessed.
Main Results:
- The iridocorneal angle remained wide post-surgery.
- Significant increases were observed in trabecular meshwork pigmentation and the number of iris processes.
- Intraocular pressure (IOP) showed a transient increase at 1 month, returning to baseline by 3 months, but significantly elevated at 6 and 12 months.
Conclusions:
- Pediatric cataract surgery leads to increased trabecular meshwork pigmentation and iris processes.
- A gradual increase in IOP post-surgery was noted, correlating with pigmentation and iris insertion.
- These findings highlight important anatomical and physiological changes after pediatric cataract surgery.
Aim:
To evaluate morphological changes in the iridocorneal angle after pediatric cataract surgery.
Methods:
Children who underwent primary infantile cataract surgery were included and 64 eyes from 41 children, including 18 with unilateral cataracts (18 eyes) and 23 with bilateral cataracts (46 eyes) were examined. All patients underwent two gonioscopic examinations to evaluate the iridocorneal angle, before the primary lens removal and before the secondary intraocular lens implantation. The anatomical changes in the iridocorneal angle and the relationship between intraocular pressure (IOP) and iridocorneal angle changes were also analyzed.
Results:
The iridocorneal angle was wide in 64 eyes before and after surgery. The trabecular meshwork pigmentation, number of iris processes in every quadrant of the iridocorneal angle, and the width of the ciliary body band in the superior and inferior quadrants at the second gonioscopic examination were significantly increased compared to those at the first examination (P<0.001, P<0.05, P<0.05, and P<0.05, respectively). IOP gradually increased at 1mo after operation, and returned to the preoperative level at 3mo. However, IOP still increased significantly at 6 and 12mo.
Conclusion:
The main changes after pediatric cataract surgery include an increase in trabecular meshwork pigmentation and number of iris processes, IOP gradually increase and has positive correlation with trabecular meshwork pigmentation and anterior insertion of iris process.
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