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learnMET: an R package to apply machine learning methods for genomic prediction using multi-environment trial data.

Cathy C Westhues1,2, Henner Simianer2,3, Timothy M Beissinger1,2

  • 1Division of Plant Breeding Methodology, Department of Crop Sciences, University of Goettingen, 37075 Goettingen, Germany.

G3 (Bethesda, Md.)
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Summary

The R-package learnMET integrates genomic and environmental data for multi-environment trial analysis using machine learning. It offers flexible tools for plant breeders to improve genomic prediction models.

Keywords:
R softwareenvironment interactiongenomic predictiongenotype ×machine learningmultienvironment trials

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Area of Science:

  • Agricultural Science
  • Bioinformatics
  • Computational Biology

Background:

  • Multi-environment trials (MET) are crucial for assessing genotype performance across diverse conditions.
  • Integrating genomic and environmental data can enhance the accuracy of plant breeding predictions.
  • Existing tools may lack flexibility in handling diverse environmental data and machine learning approaches.

Purpose of the Study:

  • To introduce learnMET, an R-package designed for comprehensive analysis of MET breeding data.
  • To provide a flexible framework for incorporating genomic, climate, and soil data into machine learning models.
  • To facilitate advanced genomic prediction and model evaluation for plant breeders.

Main Methods:

  • Development of an R-package, learnMET, offering a unified framework for MET data analysis.
  • Integration of genomic data with environmental variables, including field and NASA-sourced weather data.
  • Implementation of various machine learning algorithms (e.g., gradient boosting, random forests, MLPs) for genomic prediction.
  • Inclusion of diverse cross-validation strategies tailored for MET experimental designs.

Main Results:

  • learnMET enables the combination of diverse data types (genomic, environmental) for sophisticated analyses.
  • The package supports flexible aggregation of daily weather data using phenological or naive approaches.
  • Multiple machine learning models are available for genomic prediction, with robust evaluation schemes.
  • The package is user-friendly, aiding plant breeders in practical application.

Conclusions:

  • learnMET provides a powerful and flexible R-package for machine learning-based genomic prediction in plant breeding.
  • The integration of environmental data enhances the predictive power of breeding programs.
  • The package democratizes access to advanced analytical methods for multi-environment trial data.