Related Experiment Video
Updated: Aug 28, 2025

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy
Published on: September 28, 2019
Marginal Ulcer Perforation in a Whipple Survivor: A Rare Long-Term Complication
Arunraj P1, Kolandasamy C1, Prabhakaran R1
1Surgical Gastroenterology, Madras Medical College, Chennai, IND.
Abstract:
Long-term complications following pancreaticoduodenectomy are rarely reported because of the poor long-term survival of these patients. Marginal ulcers can occur in both the short and long term, and they can become complicated by bleeding or perforation. Marginal ulcer with perforation is a rare incidence and only sparse literature evidence is available. Herein, we report on a patient who underwent pancreaticoduodenectomy 12 years ago for duodenal adenocarcinoma and was diagnosed to have perforation peritonitis. He underwent emergency laparotomy and lavage, and omental patch closure for marginal ulcer perforation at the gastrojejunostomy site. Truncal vagotomy and feeding jejunostomy were also done.
Insights
Long-term pancreaticoduodenectomy complications are rare. This case highlights a rare marginal ulcer perforation 12 years post-surgery, emphasizing the need for vigilance in long-term patient follow-up.
Area of Science:
- Gastroenterology and Surgical Oncology
Background:
- Pancreaticoduodenectomy (Whipple procedure) is a complex surgery for upper gastrointestinal cancers.
- Long-term complications are infrequently documented due to historically poor patient survival rates.
Observation:
- A patient presented with perforation peritonitis 12 years after pancreaticoduodenectomy for duodenal adenocarcinoma.
- The perforation was identified at the gastrojejunostomy site, indicative of a marginal ulcer.
Findings:
- The patient underwent emergency laparotomy with lavage and omental patch closure for the marginal ulcer perforation.
- Surgical intervention also included truncal vagotomy and a feeding jejunostomy.
Implications:
- This case underscores the potential for rare, late-onset complications like marginal ulcer perforation after pancreaticoduodenectomy.
- It highlights the importance of continued surveillance for gastrointestinal complications in long-term survivors of this procedure.
More Related Videos
Related Concept Videos
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
