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Updated: Aug 28, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Spontaneous Acute Mesenteric Thrombosis in a Patient With Hemoglobin E Thalassemia
Joseph Asemota1, Ademola S Ojo1, Somtochukwu G Ojukwu1
1Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
Abstract:
Acute mesenteric vein thrombosis (MVT) is an uncommon cause of mesenteric ischemia and portal hypertension. The common risk factors for the development of MVT include surgery, acute-intraabdominal inflammatory disorders, malignancies, and other prothrombotic states. However, MVT can occur in the absence of these risk factors. We describe the case of a 40-year-old man with a new diagnosis of hemoglobin E thalassemia and MVT and discuss the relationship between the hemoglobinopathy and thrombosis based on evidence from existing literature. The case emphasizes the importance of a high index of suspicion in the diagnosis of MVT in other to reduce complications and improve overall outcomes.
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