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Rathke's cleft cysts: A single-center case series
Guive Sharifi1, Arsalan Amin1, Mahmoud Lotfinia2
1Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.
Surgical Neurology International
|September 21, 2022
Summary
Management of Rathke's cleft cysts (RCCs) using endoscopic endonasal transsphenoidal surgery is safe and effective. This approach resulted in minimal recurrence for 27 patients with symptomatic sellar or suprasellar lesions.
Area of Science:
- Neurosurgery
- Endocrinology
- Skull Base Surgery
Background:
- Rathke's cleft cysts (RCCs) are common benign sellar/suprasellar lesions.
- Symptomatic RCCs require effective management strategies.
Purpose of the Study:
- To report the management experience of 27 Rathke's cleft cyst cases.
- To evaluate the safety and efficacy of the endoscopic endonasal transsphenoidal approach for RCC removal.
Main Methods:
- Retrospective analysis of 27 symptomatic RCC patients (Jan 2016-Jan 2020).
- Data collected included demographics, clinical, imaging, and pathology findings.
- All patients underwent endoscopic endonasal transsphenoidal (EETS) surgery, with two exceptions.
Main Results:
- The study included 27 patients (24 women, 3 men; mean age 38).
- Headache was the most frequent symptom (74%).
- Tumors were primarily sellar (59.2%) with some suprasellar extension (33.3%).
Conclusions:
- Endoscopic endonasal transsphenoidal (EETS) surgery is a safe treatment for Rathke's cleft cysts.
- The EETS approach demonstrated minimal recurrence rates in this cohort.
