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[Brain Abscess]

Kohei Kanaya1, Tetsuyoshi Horiuchi

  • 1Department of Neurosurgery, Shinshu University School of Medicine.

No Shinkei Geka. Neurological Surgery
|September 21, 2022
PubMed

Insights

Brain abscesses, infections in the brain, are caused by various pathogens. While outcomes have improved, challenges in neurosurgery persist, impacting patient quality of life.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Neurosurgery

Background:

  • Brain abscesses are serious intracranial infections with diverse etiologies including bacteria, mycobacteria, fungi, and parasites.
  • Incidence ranges from 0.4-0.9 per 100,000, with increased risk in immunosuppressed individuals and children (approx. 25%).
  • Significant advancements in diagnostics and treatment have improved patient outcomes over the last 50 years.

Purpose of the Study:

  • To provide a comprehensive overview of brain abscesses.
  • To discuss the etiology, pathogenesis, diagnostic imaging, and treatment modalities.
  • To highlight persistent challenges in neurosurgery regarding overall outcomes and quality of life.

Main Methods:

  • Review of current literature on brain abscesses.
  • Analysis of etiological factors and pathogenesis.
  • Discussion of diagnostic imaging techniques and therapeutic strategies.

Main Results:

  • Brain abscesses result from a range of infectious agents.
  • Improved diagnostic and treatment methods have led to better prognoses.
  • Despite progress, achieving optimal outcomes and quality of life remains a neurosurgical challenge.

Conclusions:

  • Brain abscess management requires a multidisciplinary approach.
  • Continued research is needed to address long-term quality of life issues.
  • Understanding etiology, pathogenesis, and advanced treatment is crucial for neurosurgical care.

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