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Updated: Aug 28, 2025

11:27
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
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Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo
Nishanth D Tirukoti1, Liat Avram2, Reut Mashiach1
1Department of Molecular Chemistry and Materials Science, Weizmann Institute of Science, Rehovot 7610001, Israel. amnon.barshir@weizmann.ac.il.
Abstract:
An MRI-responsive agent that spontaneously self-assembles to a large supramolecular structure under physiological conditions was designed. The obtained assembly provides an extended time window for in vivo studies, as demonstrated for a fluorine-19 probe constructed to sense Zn2+ with 19F-iCEST MRI, in the future.

