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Metastasis02:30

Metastasis

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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Updated: Aug 28, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
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Ectopic papillary thyroid carcinoma mimicking distant metastatic tissue.

Yingsong Qi1, Jianwei Liu1, Ya Liu2

  • 1Department of Cardiothoracic Surgery, Chengde Central Hospital, No. 11 Guangren Road, Chengde, Hebei, People's Republic of China.

The Journal of International Medical Research
|September 21, 2022
PubMed
Summary

A rare case of ectopic intrapulmonary papillary thyroid carcinoma (PTC) co-occurring with lung adenocarcinoma was diagnosed. Recognizing ectopic thyroid tumors is crucial to prevent misdiagnosis of lung metastasis.

Area of Science:

  • Oncology
  • Pathology
  • Endocrinology

Background:

  • Lung nodules can present diagnostic challenges, often mimicking metastatic disease.
Keywords:
Ectopic thyroidbilateralcomputed tomographylung cancermetastasismultiple nodulespapillary thyroid carcinomapositron emission tomography/computed tomographysingle stagethyroidectomy

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  • Distinguishing primary lung cancer from metastatic tumors is critical for appropriate patient management.
  • Ectopic thyroid tissue in the lung is a rare entity that can complicate differential diagnoses.