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Prioritizing Pregnant Women for Coronavirus Disease 2019 Vaccination in African Countries

Jean B Nachega1,2,3, Nadia A Sam-Agudu4,5,6, Mark J Siedner7,8

  • 1Department of Epidemiology, Infectious Diseases and Microbiology, and Center for Global Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|September 21, 2022
PubMed

Insights

COVID-19 vaccination is safe and effective for pregnant African women, yet guidelines are lacking. Prioritizing vaccination and implementing public health campaigns are crucial for maternal and infant health.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Maternal Health

Background:

  • COVID-19 poses significant risks to pregnant women and infants globally.
  • Vaccine safety and efficacy data for pregnant individuals are robust.
  • African nations often have unclear or absent national guidelines regarding COVID-19 vaccination in pregnancy.

Purpose of the Study:

  • To review COVID-19 epidemiology and vaccination data for pregnant African women.
  • To identify key barriers to vaccine uptake in this demographic.
  • To propose actionable interventions to improve vaccination rates.

Main Methods:

  • Synthesis of existing epidemiological data on COVID-19 in pregnant African populations.
  • Review of evidence on COVID-19 vaccine safety and efficacy in pregnancy.
  • Analysis of national policy landscapes concerning vaccination for pregnant women in Africa.

Main Results:

  • COVID-19 vaccination is demonstrably safe and effective for pregnant women and infants.
  • Significant barriers exist, leading to suboptimal vaccine uptake.
  • Current national guidelines in many African countries are insufficient.

Conclusions:

  • Policymakers must prioritize pregnant women for COVID-19 vaccination, aiming for 100% coverage.
  • Sustained, evidence-based public health campaigns are needed to address vaccine hesitancy.
  • Vaccination services should be integrated into antenatal care and obstetrics/gynecology settings, alongside mass vaccination efforts.
  • Robust national monitoring and evaluation frameworks are essential for assessing vaccine uptake, safety, and outcomes.

Keywords:
COVID-19SARS-CoV-2pregnancysub-Saharan Africavaccination

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