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Luis García-Benítez1, Víctor Granados-García2, Marcela Agudelo-Botero3

  • 1Programa de Maestría y Doctorado en Ciencias Médicas, Odontológicas y de la Salud, Facultad de Medicina, Universidad Nacional Autónoma de México. Ciudad de México, México. luisgarbet@gmail.com.

Salud Publica De Mexico
|September 21, 2022
PubMed
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Pulse oximetry screening for critical congenital heart defects (CCHD) is cost-effective in Mexico. This method detects more CCHD cases, offering a valuable investment for child health.

Area of Science:

  • Neonatal health
  • Public health economics
  • Cardiology screening

Background:

  • Critical congenital heart defects (CCHD) are a significant cause of infant mortality.
  • Early detection of CCHD is crucial for timely intervention and improved outcomes.
  • Current screening methods in Mexico may not be fully comprehensive.

Purpose of the Study:

  • To conduct a cost-effectiveness analysis of pulse oximetry as a neonatal screening tool for CCHD in Mexico.
  • To compare the cost-effectiveness of physical examination alone versus physical examination combined with pulse oximetry screening (POP).

Main Methods:

  • An economic evaluation study was performed from the perspective of healthcare providers.
  • A decision tree model was utilized to compare screening strategies.

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  • The analysis focused on the incremental cost-effectiveness ratio (ICER) and probability of cost-effectiveness.

    • Main Results:

    • Pulse oximetry screening (POP) identified an additional 32 cases of CCHD per 10,000 newborns.
    • The incremental cost-effectiveness ratio (ICER) was 1,219 USD per additional case detected.
    • There was a greater than 90% probability of cost-effectiveness at a willingness-to-pay threshold of 25,000 USD per early detection.

    Conclusions:

    • Pulse oximetry screening demonstrates higher cost-effectiveness for neonatal cardiac screening in Mexico compared to high-income countries.
    • Implementing POP represents a cost-effective investment to improve life years in the Mexican pediatric population.
    • Neonatal pulse oximetry is an effective strategy for early CCHD detection in Mexico.