Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

37.0K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
37.0K
What is Genetic Engineering?00:49

What is Genetic Engineering?

74.8K
Overview
74.8K
Next-generation Sequencing03:00

Next-generation Sequencing

92.3K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
92.3K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

14.1K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
14.1K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

216
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
216
Synthetic Biology02:55

Synthetic Biology

4.9K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A mechanism-inspired integrated dual-frequency ultrasound transducer for cavitation-enhanced transdermal drug delivery.

Biomaterials·2026
Same author

50 MHz etched silicon holographic ultrasonic tweezers: force calibration and cell patterning.

Ultrasonics·2026
Same author

A tunable 50 MHz acoustic vortex tweezer for size-selective manipulation and cell pre-concentration.

Lab on a chip·2026
Same author

Performance Enhancement and Ultrasonic Transducer Application of Bi/Li Codoped Ba<sub>0.95</sub>Ca<sub>0.05</sub>Ti<sub>0.95</sub>Zr<sub>0.05</sub>O<sub>3</sub> Lead-Free Ceramics.

ACS applied materials & interfaces·2026
Same author

Rapid rescue of despair behaviors by sonogenetic neuromodulation of the mPFC-DRN pathway.

Molecular psychiatry·2026
Same author

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Related Experiment Video

Updated: Aug 28, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

33.9K

Sonogenetics: Recent advances and future directions.

Tianyi Liu1, Mi Hyun Choi2, Jiejun Zhu1

  • 1Guangdong Institute of Intelligence Science and Technology, Hengqin, Zhuhai, Guangdong, 519031, China.

Brain Stimulation
|September 21, 2022
PubMed
Summary
This summary is machine-generated.

Sonogenetics uses ultrasound to control neural activity noninvasively. This review highlights cleared technical hurdles and remaining challenges for optimizing this promising tool for neural circuit studies.

More Related Videos

Generation of Genetically Modified Mice through the Microinjection of Oocytes
10:19

Generation of Genetically Modified Mice through the Microinjection of Oocytes

Published on: June 15, 2017

20.8K
Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells
09:20

Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells

Published on: July 6, 2021

2.5K

Related Experiment Videos

Last Updated: Aug 28, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

33.9K
Generation of Genetically Modified Mice through the Microinjection of Oocytes
10:19

Generation of Genetically Modified Mice through the Microinjection of Oocytes

Published on: June 15, 2017

20.8K
Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells
09:20

Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells

Published on: July 6, 2021

2.5K

Area of Science:

  • Neuroscience
  • Biotechnology
  • Biomedical Engineering

Background:

  • Sonogenetics enables noninvasive neural activity control using genetically encoded ultrasound-responsive mediators.
  • It offers a promising approach for studying complex neural circuits with high precision.

Purpose of the Study:

  • To review recent advancements in sonogenetics.
  • To identify technical hurdles overcome and remaining challenges.
  • To outline future directions for optimizing sonogenetics.

Main Methods:

  • Literature review of recent findings in sonogenetics.
  • Analysis of key in vivo performance metrics: spatiotemporal resolution, selectivity, specificity, and safety.

Main Results:

  • Sonogenetics has demonstrated significant progress in noninvasive neural control.
  • Key technical hurdles in sonogenetics have been addressed.
  • Further optimization is needed to fully realize its potential in neuroscience research.

Conclusions:

  • Sonogenetics is a rapidly developing field with the potential to revolutionize neural circuit research.
  • Addressing current challenges will enhance its efficacy and broaden its applications.
  • Continued research is crucial for optimizing sonogenetics' performance and safety.