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Updated: Jul 28, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Case report: Use of unenhanced cardiac MR to evaluate low flow states for thrombus
Avinoam Levin1, Raphael Miller1, Nidhish Tiwari2
1Department of Radiology, Jacobi Medical Center, 1400 Pelham Pkwy S, The Bronx, NY 10461, USA.
Insights
Left atrial spontaneous echo contrast on echocardiography and cardiac MRI can mimic thrombus. Cardiac MRI can differentiate non-thrombotic low flow states, especially when contrast is contraindicated.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Echocardiography
Background:
- Left atrial spontaneous echo contrast (LASEC) on echocardiography is linked to hypercoagulable states and stasis.
- LASEC can indicate thromboembolism risk in patients with atrial fibrillation, mitral stenosis, or mitral valve repair.
Observation:
- A 66-year-old woman with persistent atrial fibrillation presented with LASEC and high signal on black blood double inversion recovery cardiac magnetic resonance imaging (BBDISC-CMR).
- These findings raised concern for an intracardiac thrombus.
Findings:
- Subsequent bright blood cardiac magnetic resonance imaging (BB-CMR) revealed high signal with transient central swirling low signal in the left atrium.
- This pattern ruled out a thrombus, indicating a non-thrombotic low flow state.
Implications:
- Cardiac MRI can effectively differentiate between thrombus and non-thrombotic low flow states in the left atrium.
- This is particularly crucial in patients with contraindications to contrast agents, such as those with atrial fibrillation.
Abstract:
Left atrial spontaneous echo contrast is an echocardiographic finding associated with hypercoagulable states and stasis and can be clinically correlated with a thromboembolism in patients with atrial fibrillation, mitral stenosis, or mitral valve repair. Black blood double inversion recovery cardiac magnetic resonance is used to map out cardiac anatomy and demonstrates higher signal in blood flowing at a slower rate, such as at the sites of aortic aneurysms, aortic dissections and vessel occlusions. Here, we present the case of a 66-year-old woman with persistent atrial fibrillation and left atrial findings of spontaneous echo contrast and high signal on black blood double inversion recovery cardiac magnetic resonance imaging, raising concern for a thrombus. However, this was ruled out with subsequent bright blood cardiac magnetic resonance imaging demonstrating high signal with transitory central swirling low signal in the left atrium. Thus, cardiac magnetic resonance imaging can be used to demonstrate non-thrombotic low flow states in cases where contrast is contraindicated.
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