Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of light intensity on the growth and photosynthetic physiology of Zelkova schneideriana seedlings.

BMC plant biology·2026
Same author

Intermetallic nanoassemblies potentiate systemic STING activation.

Science (New York, N.Y.)·2026
Same author

Pharmacokinetics and Safety of Single and Multiple Doses of Molnupiravir in Healthy Male Chinese Adults: An Open-Label, Fixed Sequence, Phase 1 Study.

Clinical and translational science·2026
Same author

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous Administration JMKX003142 in Chinese Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Single, and Multiple Ascending Dose Phase I Clinical Trial.

Drug design, development and therapy·2026
Same author

The phosphate-solubilizing capacity of Rhizobium tropici LNP6 and its growth-promoting effects on Ormosia hosiei seedlings.

BMC plant biology·2026
Same author

Diffusing capacity for carbon monoxide is significantly associated with cardiovascular disease-related plasma proteins, independently of obstruction.

Clinical proteomics·2026
Same journal

Facile fabrication of hollow carbon nanomaterials by directed polymerization of butadiyne on the surface of reverse micelles.

Nanoscale advances·2026
Same journal

Investigation of the chemical structure of core-shell Fe<sub>3</sub>O<sub>4</sub>@Ni<sub>1-<i>x</i></sub> Co <sub><i>x</i></sub> Fe<sub>2</sub>O<sub>4</sub> nanoparticles and its influence on their magnetic properties.

Nanoscale advances·2026
Same journal

Simple CsI doping outperforms complex organic additives in carbon-based perovskite solar cells.

Nanoscale advances·2026
Same journal

Photoelectrochemically homogeneous nickel oxide photocathode composed of nanocrystals prepared by supercritical hydrothermal synthesis.

Nanoscale advances·2026
Same journal

Evidence of dipolar magnetic interactions in the self-assembly of two-dimensional magnetic nanocubes.

Nanoscale advances·2026
Same journal

Effect of sputter-coated platinum on the photostability of nanoporous sol-gel CuO thin film photocathodes.

Nanoscale advances·2026
See all related articles

Related Experiment Video

Updated: Aug 28, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.5K

Microneedle-based bioassays.

Jixiang Zhu1,2, Xingwu Zhou1, Alberto Libanori1

  • 1Department of Bioengineering, Center for Minimally Invasive Therapeutics (C-MIT), University of California, Los Angeles Los Angeles CA 90095 USA sunwj@ucla.edu.

Nanoscale Advances
|September 22, 2022
PubMed
Summary
This summary is machine-generated.

Microneedles (MNs) offer a less painful way to collect body fluids for disease diagnosis. This review explores MN-based bioassays for improved health monitoring and diagnostics.

More Related Videos

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

2.2K
Absorbent Microbiopsy Sampling and RNA Extraction for Minimally Invasive, Simultaneous Blood and Skin Analysis
06:18

Absorbent Microbiopsy Sampling and RNA Extraction for Minimally Invasive, Simultaneous Blood and Skin Analysis

Published on: February 21, 2019

10.0K

Related Experiment Videos

Last Updated: Aug 28, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.5K
Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

2.2K
Absorbent Microbiopsy Sampling and RNA Extraction for Minimally Invasive, Simultaneous Blood and Skin Analysis
06:18

Absorbent Microbiopsy Sampling and RNA Extraction for Minimally Invasive, Simultaneous Blood and Skin Analysis

Published on: February 21, 2019

10.0K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Clinical Diagnostics

Background:

  • Traditional bioassays for disease diagnosis and monitoring require invasive body fluid extraction, causing pain and needing specialized equipment.
  • Current bioassay methods are often complex, painful, and require trained medical professionals, highlighting the need for less invasive alternatives.
  • Microneedles (MNs) are emerging as a minimally invasive, painless, and simple alternative for body fluid sampling.

Purpose of the Study:

  • To review and categorize microneedle (MN)-based platforms for disease detection and diagnosis.
  • To discuss the design principles and mechanisms of MN-based bioassay platforms.
  • To explore the challenges and future opportunities for MN-based bioassays in clinical settings.

Main Methods:

  • Categorization of MN-based bioassay platforms based on their functional mechanisms: body fluid reservoirs, electrochemical assays, and colorimetric analyses.
  • Review of recent advancements in microfabrication and materials engineering for MN development.
  • Analysis of design principles for effective MN-based bioassay platforms.

Main Results:

  • Microneedle-based platforms show significant promise for minimally invasive bioassays.
  • Three main categories of MN-based bioassays have been identified: fluid reservoirs, electrochemical, and colorimetric.
  • Progress in microfabrication and materials science enables advanced MN architectures and functionalities.

Conclusions:

  • Microneedle-based bioassays represent a significant advancement over traditional methods for disease diagnosis and monitoring.
  • Further development and clinical validation are needed to overcome challenges and realize the full potential of MN-based bioassays.
  • MN platforms offer a promising future for accessible, patient-friendly diagnostic tools.