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Published on: November 4, 2010
Risk Factors of Childhood Asthma Among Patients Attending a Tertiary Care Centre in North-East India
Himamoni Deka1, Putul Mahanta2, Sultana Jesmin Ahmed3
1Depatment of Anatomy, Gauhati Medical College, Guwahati, Assam, India.
Insights
Childhood asthma is linked to urban living, damp environments, and family history. Awareness and preventive measures are crucial for reducing asthma
Area of Science:
- Pediatric Allergy and Immunology
- Environmental Health
- Epidemiology
Background:
- Asthma is a chronic respiratory condition with increasing prevalence.
- Both genetic predisposition and environmental exposures contribute to asthma development.
- Childhood asthma poses a significant public health burden, necessitating research into its causative factors.
Purpose of the Study:
- To investigate the socio-demographic and environmental factors associated with childhood asthma.
- To identify risk factors for childhood asthma in patients attending Gauhati Medical College and Hospital, Assam.
Main Methods:
- A case-control study involving 150 children aged 3-12 years with asthma and 150 healthy controls.
- Data collection using a predesigned questionnaire, with informed consent from guardians.
- Statistical analysis including chi-square test and binary logistic regression.
Main Results:
- Urban locality, male gender, and damp environments were significant risk factors for childhood asthma.
- Lower socioeconomic status, presence of pets, family history of atopy/allergy, passive smoking, and mixed feeding were also associated with increased asthma risk.
- Odds ratios indicated significant associations for urban living (OR=4.53), damp environment (OR=5.21), lower socioeconomic status (OR=3.48), pets (OR=6.77), family history (OR=43.29), smoking (OR=23.54), and mixed feeding (OR=4.47).
Conclusions:
- Environmental and socio-demographic factors play a critical role in the causation of childhood asthma.
- Children are particularly susceptible to environmental triggers for asthma.
- Increased awareness and targeted preventive strategies are essential to mitigate the impact of childhood asthma.
Introduction:
Asthma is a chronic lung illness marked by a reversible airway blockage. Both genetic and environmental factors influence higher asthma rates. The present study aims to assess the various socio-demographic and environmental factors influencing the causation of childhood asthma among patients attending the Paediatric Department of Gauhati Medical College and Hospital (GMCH), Assam.
Materials And Methods:
A total of 150 clinically diagnosed asthma patients of 3-12 years as cases and patients of the same age group free from respiratory diseases with no history of asthma in a 1:1 ratio as controls were selected. A predesigned and pretested proforma was used to collect data, and written informed consent was obtained from all the legal guardians of the participants. Data were analyzed by chi-square test and binary logistic regression using SPSS V20, considering a p-value <0.05 significant.
Results:
Urban and male children were found to be at higher risk of developing asthma. Children belonging to the urban locality (OR= 4.53; 95% CI: 1.57-13.09; p<0.05), damp environment (OR= 5.21; 95% CI: 1.23-22.10; p<0.05), lower socioeconomic status (OR= 3.48; 95% CI: 1.34-9.01; p<0.05), presence of pets (OR= 6.77; 95% CI: 1.76-25.99; p<0.05), family history of atopy/ allergy (OR= 43.29; 95% CI: 5.80-323.15 p<0.05), smoking/passive smoking (OR=23.54; 95% CI: 1.41-394.21 p<0.05) and mixed feeding (OR= 4.47; 95% CI: 1.46-13.63 p<0.05) were the significant risk factors of childhood asthma.
Conclusion:
Children are vulnerable to environmental-induced asthma. Awareness and preventive measures are necessary to control and reduce the burden of childhood asthma.
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