Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bis-α,ω-bisacylphosphane oxides: simple access to crosslinked polymers with tunable properties.

Journal of materials chemistry. A·2026
Same author

Optimization of Culture Conditions for Pyrroloquinoline Quinone-Overproducing Mutant <i>Hyphomicrobium denitrificans</i> and Its Skin Bioactive Properties.

Journal of microbiology and biotechnology·2026
Same author

Hybrid Multiphoton Lithography Scaffolds for Nanoscale Mechanobiological Assessment in Microscale Bone Models.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Thiol-Yne Photocurable Isosorbide-Derived Networks: Formulation and 3D Printing.

ACS sustainable chemistry & engineering·2026
Same author

Single molecule force spectroscopy for evaluating inhibitors of SARS-CoV-2 variants of concern.

European biophysics journal : EBJ·2026
Same author

Comparative Analysis of Two Measurement Modalities for Ex Vivo Analysis of Corneal Stiffness in Porcine Corneas.

Bioengineering (Basel, Switzerland)·2025

Related Experiment Video

Updated: Aug 28, 2025

Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions
07:38

Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions

Published on: June 7, 2024

1.7K

3D multiphoton lithography using biocompatible polymers with specific mechanical properties.

Boris Buchroithner1, Delara Hartmann2, Sandra Mayr1

  • 1University of Applied Sciences Upper Austria, School of Medical Engineering and Applied Social Sciences Garnison Str. 21 4020 Linz Austria jaroslaw.jacak@fh-linz.at.

Nanoscale Advances
|September 22, 2022
PubMed
Summary
This summary is machine-generated.

Researchers developed new biocompatible polymers for 3D scaffolds using multiphoton lithography. These materials exhibit favorable mechanical properties and support endothelial cell growth, indicating potential for tissue engineering applications.

More Related Videos

Control of Cell Geometry through Infrared Laser Assisted Micropatterning
11:04

Control of Cell Geometry through Infrared Laser Assisted Micropatterning

Published on: July 10, 2021

3.5K
Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture
10:49

Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture

Published on: July 10, 2013

15.2K

Related Experiment Videos

Last Updated: Aug 28, 2025

Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions
07:38

Author Spotlight: Modular Neuronal Networks for Analyzing Brain Functions

Published on: June 7, 2024

1.7K
Control of Cell Geometry through Infrared Laser Assisted Micropatterning
11:04

Control of Cell Geometry through Infrared Laser Assisted Micropatterning

Published on: July 10, 2021

3.5K
Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture
10:49

Printing Thermoresponsive Reverse Molds for the Creation of Patterned Two-component Hydrogels for 3D Cell Culture

Published on: July 10, 2013

15.2K

Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Tissue Engineering

Background:

  • Fabricating scaffolds that mimic the extracellular matrix is crucial for regenerative medicine.
  • Developing advanced materials for cell stimulation and support is an ongoing challenge.

Purpose of the Study:

  • To introduce two novel biocompatible polymers for scaffold fabrication.
  • To characterize the mechanical properties and biocompatibility of these new polymers.

Main Methods:

  • Multiphoton lithography was used for 3D structuring of the polymers.
  • Atomic force microscopy determined mechanical properties (Young's modulus).
  • Human umbilical vein endothelial cells were cultured to assess biocompatibility.

Main Results:

  • Polymers were successfully 3D structured with sub-micron features.
  • Young's modulus values were found to be in the 100 MPa range.
  • Endothelial cells showed good density and low apoptosis on the 2D structured substrates.

Conclusions:

  • The new polymers are suitable for creating 3D scaffolds via multiphoton lithography.
  • The materials possess suitable mechanical properties for biological applications.
  • The polymers demonstrate good biocompatibility, supporting endothelial cell viability.