Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Technological Singularity in Biomedical Science and Engineering.

Cellular and molecular bioengineering·2026

Same author

Improved latitudinal carbon budgets from global airborne surveys.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

<i>PDK4</i> as a metabolic biomarker of chronic hydrocephalus.

Frontiers in genetics·2026

Same author

Effect of graphene on the conformation and dynamics of atactic polystyrene in toluene.

Journal of molecular modeling·2026

Same author

Radiofrequency regulates the BET-mediated pathways in radial glia differentiation in human cortical development.

Cell reports·2025

Same author

NFκB1: a common biomarker linking Alzheimer's and Parkinson's disease pathology.

Frontiers in neuroscience·2025

Search research articles

Related Experiment Video

Updated: Aug 28, 2025

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

Rotaxane nanomachines in future molecular electronics.

Peiqiao Wu¹, Bhushan Dharmadhikari², Prabir Patra³

¹Department of Computer Science and Computer Engineering, University of Bridgeport Bridgeport CT USA peiqiaow@my.bridgeport.edu.

Nanoscale Advances

|September 22, 2022

Summary

Rotaxanes, mechanically interlocked molecules, show promise as molecular switches for advanced electronics. This review details their application in molecular circuits, addressing challenges for system-level integration.

More Related Videos

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

Related Experiment Videos

Last Updated: Aug 28, 2025

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

Area of Science:

Materials Science
Nanotechnology
Molecular Electronics

Background:

The electronics industry seeks novel organic molecules for high-efficiency logic circuits and memory devices.
Rotaxanes, with their mechanically interlocked structure, are emerging as potential nanomaterials for molecular switches and memory applications.
The reversible movement of rotaxane's macrocycle between stations creates distinct 'ON' and 'OFF' states with varying resistance.

Purpose of the Study:

To comprehensively review rotaxanes and their applications in molecular electronics.
To present challenges in developing rotaxane-based molecular circuits and systems at multiple levels.
To explore design considerations for voltage-driven rotaxane switches and their integration into circuits.

Main Methods:

Review and synthesis of existing research on rotaxane structure, properties, and function.
Analysis of rotaxane electrical characteristics and driving methods.
Examination of integration strategies and limitations for rotaxane molecules in electronic devices.
Investigation of sandwiched crossbar structures for rotaxane circuit architecture.

Main Results:

Voltage-driven rotaxane switches offer promising performance and compatibility with solid-state circuits.
Integration solutions and identified limitations are crucial for active molecular switch functionality.
Sandwiched crossbar architectures simplify fabrication and enable reprogrammable rotaxane arrays.

Conclusions:

Rotaxanes are viable candidates for molecular switches and memory applications in advanced electronics.
Addressing fabrication and integration challenges is key to realizing system-level rotaxane circuits.
Further development of rotaxane-based architectures promotes the advancement of molecular electronics.