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Updated: Aug 28, 2025
08:05
Detection and Isolation of Cancer in Prostate Biopsies Using Stimulated Raman Histology and Artificial Intelligence
Published on: June 10, 2025
165
The rapid assessment for prostate imaging and diagnosis (RAPID) prostate cancer diagnostic pathway
David Eldred-Evans1,2, Martin J Connor1,2, Mariana Bertoncelli Tanaka1,2
1Imperial Prostate, Division of Surgery, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
BJU International
|September 22, 2022
Summary
The Rapid Assessment for Prostate Imaging and Diagnosis (RAPID) pathway enables 43% of men to avoid prostate cancer biopsy. This standardized approach maintains high detection rates for clinically significant cancers while reducing patient burden.
Area of Science:
- Urology
- Oncology
- Diagnostic Imaging
Background:
- Prostate cancer diagnosis relies on multiparametric magnetic resonance imaging (mpMRI) and biopsy.
- Standardizing the diagnostic pathway can reduce patient and healthcare burdens.
Purpose of the Study:
- To evaluate the outcomes of the Rapid Assessment for Prostate Imaging and Diagnosis (RAPID) pathway.
- To assess the impact of RAPID on biopsy rates, cancer detection, and time to diagnosis.
Main Methods:
- A prospective registry of 2130 patients on the RAPID pathway was compared to a pre-RAPID cohort of 2435 patients.
- Biopsy recommendations were based on MRI scores and PSA density.
- Transperineal biopsy techniques and patient satisfaction were analyzed.
Main Results:
- 43% of patients on the RAPID pathway avoided biopsy.
- Clinically significant cancer detection rate was 26%.
- Time to diagnosis was reduced from 32.1 days (pre-RAPID) to 15.9 days (RAPID).
Conclusions:
- The RAPID pathway effectively reduces unnecessary biopsies while ensuring detection of significant prostate cancers.
- The pathway standardizes care, improves efficiency, and maintains high patient satisfaction.
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