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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Related Experiment Video

Updated: Aug 28, 2025

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery
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Epilepsy surgery program in a resource-limited setting in Vietnam: A multicentered collaborative model.

Viet-Thang Le1,2, Minh-An Thuy Le3,4, Duc Hue Nguyen5

  • 1Department of Neurosurgery, University Medical Center at Ho Chi Minh City, Ho Chi Minh City, Vietnam.

Epilepsia Open
|September 22, 2022
PubMed
Summary

Epilepsy surgery in Vietnam demonstrated positive outcomes, with 82.8% of patients achieving excellent seizure control (Engel Class I). This multicentered program highlights successful epilepsy surgery in resource-limited settings.

Keywords:
drug-resistantepilepsy surgerylimited-resourcemultidisciplinary team

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Area of Science:

  • Neurology
  • Neurosurgery
  • Epileptology

Background:

  • Epilepsy surgery is highly effective for drug-resistant epilepsy but remains underutilized globally.
  • Establishing epilepsy surgery programs in low- and middle-income countries is crucial for improving patient outcomes.

Purpose of the Study:

  • To evaluate the outcomes of a newly established epilepsy surgery program in Ho Chi Minh City (HCMC), Vietnam.
  • To assess the feasibility and effectiveness of a multicentered, collaborative approach in a resource-limited setting.

Main Methods:

  • A multidisciplinary team was formed in HCMC, including neurologists, neurosurgeons, and neuropsychologists.
  • Presurgical evaluations were conducted for drug-resistant epilepsy patients with identified epileptogenic lesions.
  • Epilepsy surgeries were performed between 2018 and 2021, with patients followed up for at least 12 months.

Main Results:

  • 35 out of 52 evaluated patients underwent epilepsy surgery.
  • 82.8% of operated patients achieved excellent seizure control (Engel Class I), and 17.2% achieved good seizure control (Engel Class II).
  • Successful surgical outcomes were achieved through both standard and advanced presurgical evaluations, including intraoperative electrocorticography.

Conclusions:

  • A multicentered epilepsy surgery program utilizing a collaborative model can achieve favorable outcomes in resource-limited settings.
  • The HCMC epilepsy surgery program demonstrates the potential for successful implementation and positive patient results in Vietnam.