Impact of COVID-19 infection on the dialysis population prospective, observational, nationwide study

Ali AlSahow1, Ahmed AlQallaf2, Anas AlYousef3

  • 1Division of Nephrology, Jahra Hospital, Jahra, Kuwait. alsahow@hotmail.com.

Insights

Patients on hemodialysis (HD) face higher COVID-19 mortality risks. This study analyzed 141 infected HD patients in Kuwait, finding a significant mortality rate within this vulnerable group, especially those requiring intensive care.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Epidemiology

Background:

  • Patients undergoing hemodialysis (HD) exhibit elevated susceptibility to severe COVID-19.
  • Significant variability exists in COVID-19 infection rates among HD patients.
  • Understanding mortality factors in this population is crucial for public health strategies.

Purpose of the Study:

  • To characterize COVID-19 positive hemodialysis patients in Kuwait.
  • To determine COVID-19 infection rates within the HD population.
  • To identify factors associated with mortality among HD patients with COVID-19.

Main Methods:

  • Prospective data collection from March to July 2020.
  • Analysis included demographics, comorbidities, and treatments of hospitalized HD patients with COVID-19.
  • Mortality data for HD patients with COVID-19 was systematically recorded.

Main Results:

  • 141 HD patients were admitted with COVID-19, representing 7% of the HD population and 0.2% of all COVID-19 cases.
  • Mortality rate among infected HD patients was 19% (27 deaths), accounting for 6% of total COVID-19 deaths.
  • Patients requiring continuous kidney replacement therapy (CKRT) or intensive care had higher mortality rates (34% and 65% respectively).

Conclusions:

  • Despite representing a small fraction of the total population, COVID-19 positive HD patients constitute a substantial proportion of COVID-19 cases and mortality.
  • The HD population experiences a disproportionately high COVID-19 related mortality rate.
  • Urgent attention and targeted interventions are needed for this high-risk group.
Abstract

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