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Pancreatic Adenocarcinoma Management
Yan Jiang1, Davendra P S Sohal1
1University of Cincinnati, Cincinnati, OH.
JCO Oncology Practice
|September 22, 2022
Summary
Pancreatic ductal adenocarcinoma (PDAC) management now emphasizes neoadjuvant therapy to improve surgical outcomes. Advances include FOLFIRINOX, gemcitabine with nab-paclitaxel, and targeted therapies for select patients.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Oncology
Background:
- Pancreatic ductal adenocarcinoma (PDAC) management has significantly evolved.
- Surgical resection is the only potential cure for PDAC.
- Neoadjuvant therapy is increasingly emphasized to improve resectability and early failure detection.
Conclusions:
- Modern PDAC management integrates neoadjuvant strategies to enhance surgical success.
- Chemotherapy regimens like FOLFIRINOX and gemcitabine/nab-paclitaxel are crucial.
- Future PDAC treatment will likely be guided by ongoing clinical trials and personalized molecular approaches.
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