Related Experiment Video
Updated: Aug 28, 2025

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Effectiveness of Indirect and Direct Laryngoscopes in Pediatric Patients: A Systematic Review and Network
Hiroshi Hoshijima1, Takahiro Mihara2, Shinichi Kokubu3
1Division of Dento-Oral Anesthesiology, Graduate School of Dentistry, Tohoku University, Sendai 980-8575, Japan.
Insights
Network meta-analysis ranked pediatric intubation devices. No device surpassed the Macintosh laryngoscope for first-attempt intubation success or glottic visualization in children.
Area of Science:
- Pediatric Anesthesiology
- Medical Device Technology
- Clinical Effectiveness Research
Background:
- Effective tracheal intubation is critical in pediatric care.
- Varied intubation devices exist, but comparative effectiveness data is limited.
- Ranking device performance is essential for clinical decision-making.
Purpose of the Study:
- To systematically rank the effectiveness of various tracheal intubation devices in pediatric patients.
- To compare first-attempt intubation failure rates, glottic visualization, and intubation times.
- To utilize network meta-analysis (NMA) for a comprehensive effectiveness assessment.
Main Methods:
- A systematic search of electronic databases for prospective randomized trials comparing pediatric tracheal intubation devices.
- Network meta-analysis (NMA) using DerSimonian and Laird random-effects models.
- Evaluation of primary outcome (first-attempt intubation failure) and secondary outcomes (glottic visualization, intubation time).
Main Results:
- Thirty-four trials involving 13 devices were analyzed.
- Most devices showed similar first-attempt intubation failure rates to the Macintosh laryngoscope.
- The Truview PCD™ demonstrated a significantly higher failure rate; Airtaq™, AirwayScope™, McGrath™, and Truview EVO2™ ranked higher than Macintosh. Bullard™ ranked lowest.
- Glottic visualization was comparable across devices; C-MAC™ offered shorter intubation times, while GlideScope™, Storz DCI™, Truview PCD™, and Bullard™ had longer times.
Conclusions:
- Network meta-analysis provides a coherent ranking of pediatric intubation device effectiveness.
- Currently, no laryngoscope appears superior to the Macintosh laryngoscope for pediatric first-attempt intubation success and glottic visualization.
- Device selection should consider specific outcomes like intubation time and failure rates.
Abstract:
This research aimed to produce a coherent ranking of the effectiveness of intubation devices in pediatric patients using network meta-analysis (NMA). We searched the electric databases for prospective randomized studies that compared different tracheal intubation devices in pediatric patients. The primary outcome was intubation failure at the first attempt. Secondary outcomes were glottic visualization and intubation time. The statistical analysis performed used DerSimonian and Laird random-effects models. Frequentist network meta-analysis was conducted, and network plots and network league tables were produced. Subgroup analysis was performed after excluding rigid-fiberscope-type indirect laryngoscopes. Thirty-four trials comparing 13 devices were included. Most laryngoscopes had the same intubation failure rate as the Macintosh reference device. Only the Truview PCD™ had a significantly higher intubation failure rate than the Macintosh (odds ratio 4.78, 95% confidence interval 1.11-20.6) The highest-ranking laryngoscope was the Airtaq™ (P score, 0.90), and the AirwayScope™, McGrath™, and Truview EVO2™ ranked higher than the Macintosh. The Bullard™ had the lowest ranking (P score, 0.08). All laryngoscopes had the same level of glottic visualization as the Macintosh and only the C-MAC™ had a significantly shorter intubation time. Intubation time was significantly longer when using the GlideScope™, Storz DCI™, Truview PCD™, or Bullard™ compared with the Macintosh. P score and ranking of devices in the subgroup analyses were similar to those in the main analysis. We applied NMA to create a consistent ranking of the effectiveness of intubation devices in pediatric patients. The findings of NMA suggest that there is presently no laryngoscope superior to the Macintosh laryngoscope in terms of tracheal intubation failure rate and glottic visualization in pediatric patients.
Related Concept Videos
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Cardiopulmonary Resuscitation II: ACLS Airway Management
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Endotracheal Intubation I: Procedure
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...

