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Typical Enhancers, Super-Enhancers, and Cancers

Marianna A Koutsi1, Marialena Pouliou1, Lydia Champezou1

  • 1Center of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., 11527 Athens, Greece.

Cancers
|September 23, 2022
PubMed
Summary

Genomic variations in cancer disrupt enhancers and Super-enhancers, altering gene expression. This study explores these mechanisms, technologies, and treatments for aberrant Super-enhancer function.

Keywords:
Next-Generation Sequencing (NGS)Super-enhancers (SEs)cancerchromatinenhancersepigeneticsgene expression programsgenomic variationsoncogenestranscription factors (TFs)tumorigenesis

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