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MET Oncogene Controls Invasive Growth by Coupling with NMDA Receptor

Simona Gallo1,2, Annapia Vitacolonna1,2, Paolo Comoglio3

  • 1Department of Oncology, University of Turin, Strada Provinciale 142, 10060 Candiolo, Italy.

Cancers
|September 23, 2022
PubMed
Summary

Researchers found a link between MET and the N-methyl-D-aspartate receptor (NMDAR) in triple-negative breast cancer. Inhibiting NMDAR reduces the invasive growth driven by MET signaling, suggesting a new therapeutic approach.

Keywords:
MET tyrosine kinase receptorglutamate receptorhepatocyte growth factortumor invasion

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