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Updated: Aug 28, 2025

Human Egg Maturity Assessment and Its Clinical Application
Published on: August 19, 2019
Methods for Assessing Oocyte Quality: A Review of Literature
Yassir Lemseffer1,2, Marie-Emilie Terret3, Clément Campillo4
1Hospices Civils de Lyon, Service de Médecine de la Reproduction, 59 Bd. Pinel, 69500 Bron, France.
Abstract:
The rate of infertility continues to rise in the world for several reasons, including the age of conception and current lifestyle. We list in this paper potential non-invasive and invasive techniques to assess oocyte quality. We searched the database PubMed using the terms "oocytes AND quality AND evaluation". In the first part, we study the morphological criteria, compartment by compartment, to then focus in a second part on more objective techniques such as genetics, molecular, apoptosis, or human follicular fluid that contain biologically active molecules. The main criteria used to assess oocyte quality are morphological; however, several other techniques have been studied in women to improve oocyte quality assessment, but most of them are invasive and not usable in routine.

