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Related Experiment Video

Updated: Aug 28, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
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Segmentation-Based Classification Deep Learning Model Embedded with Explainable AI for COVID-19 Detection in Chest

Nillmani1, Neeraj Sharma1, Luca Saba2

  • 1School of Biomedical Engineering, Indian Institute of Technology (BHU), Varanasi 221005, India.

Diagnostics (Basel, Switzerland)
|September 23, 2022
PubMed
Summary

A new deep learning system for COVID-19 detection using chest X-rays achieved high accuracy. This segmentation-based classification approach shows promise for clinical use with an error rate below 5%.

Keywords:
COVID-19UNetXceptionchest X-rayclassificationdeep learningerror rateprecisionregulatorysegmentation

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Deep Learning

Background:

  • Current COVID-19 detection methods using chest X-rays have high error rates, limiting clinical application.
  • Accurate and rapid COVID-19 diagnosis is crucial for patient management and public health.

Purpose of the Study:

  • To develop and evaluate deep learning models for accurate COVID-19 detection in chest X-rays.
  • To achieve a segmentation-based classification error rate below 5% for clinical adaptability.

Main Methods:

  • Proposed 16 segmentation-based classification deep learning systems combining UNet/UNet+ with 8 classification models.
  • Evaluated performance using Dice, Jaccard, AUC, ROC, and Grad-CAM for explainability.

Main Results:

  • The UNet segmentation model achieved 96.35% accuracy, 94.88% Dice, and 90.38% Jaccard index.
  • The UNet+Xception model demonstrated superior performance with 97.45% accuracy and 0.998 AUC.
  • The proposed system outperformed existing methods by an average of 8.27%.

Conclusions:

  • Segmentation-based classification deep learning models are effective for COVID-19 detection.
  • The developed system meets the <5% error rate threshold, making it suitable for clinical settings.